University of Toronto/Kensington Health Ophthalmology Cytokine and Imaging Laboratory
As medicine transitions to personalized healthcare, there will be increasing interest in novel biomarkers that can predict disease severity and treatment response. We believe that ocular fluid cytokine levels together with novel imaging biomarkers may provide valuable information that can help manage a variety of ocular diseases. Our goal is to obtain a molecular fingerprint that together with imaging and clinical data can enable truly individualized care in various key areas in ophthalmology. To this extent, the University of Toronto Department of Ophthalmology and Vision Sciences and the Kensington Research Institute have established the Ophthalmology Biobank. The Biobank will store ocular fluid samples from a variety of patients undergoing procedures and surgeries. This unique Ophthalmology Cytokine and Imaging Laboratory at Kensington Eye Institute will primarily focus on cytokine analysis from ocular fluids and the development and validation of novel imaging biomarkers. This laboratory is one of a kind in Canada and likely the world with specialized equipment to measure ocular fluid cytokines with multiplex immunoassays and the latest imaging tools such as an adaptive optics retinal camera. The Cytokine & Imaging Lab together with the Biobank will support the development of tools and protocols to analyze ocular fluids and assess the associations with a variety of clinical outcomes. Initial studies and protocols have been developed for a variety of retinal and corneal diseases with a planned rapid expansion to all areas in ophthalmology. We feel strongly that research from this lab will lead to better patient outcomes with targeted delivery of health care that is also cost-effective.
Medical Director: Rajeev Muni, MD, MSc., FRCS(C), FASRS
Manager of Research Operations: Mano Chandrakumar, MSc., MBA